A 12-year-old athlete prescribed a statin sparked a deeper question: are we treating numbers or people? This letter unpacks ...

Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium release (CICR) without affecting depolarization-induced calcium release. The ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

From the microscopic dance of actin and myosin to the full-body power you feel in a workout, muscle contraction is a precise, coordinated process. It starts with a nerve signal, triggers calcium ...

Biomedical engineers have grown muscles in a lab to better understand and test treatments for a group of extremely rare muscle disorders called dysferlinopathy or limb girdle muscular dystrophies 2B ...

We are at a critical time and supporting science journalism is more important than ever. Science News and our parent organization, the Society for Science, need your help to strengthen scientific ...

Muscle contraction is the tightening, shortening, or lengthening of muscles when you do some activity. It can happen when you hold or pick up something, or when you stretch or exercise with weights.

The top row of photos show a microscopic view of healthy muscle fibers stained to reveal a variety of irregularities, while the bottom row shows the same but for muscle fibers afflicted by the disease ...