In a recent study published in Nature Communications, researchers examinea the effects of temporal morphogen gradient during neural induction (NI) on the formation of brain organoids. Study: Temporal ...

Discover the first images of cytonemes during mammalian neural development, serving as express routes to establish morphogen gradients and tissue patterning. St. Jude Children's Research Hospital ...

Human neural organoids, derived from pluripotent stem cells, enable the study of the highly regulated process of human brain development in vitro. In vivo, the process is shaped by strict time- and ...

Just a few weeks after conception, stem cells are already orchestrating the future structure of the human brain. A new Yale-led study shows that, early in development, molecular “traffic cops” known ...

Cells producing noise in the Wnt morphogen gradient are sensed by neighboring cells through E-cadherin and then eliminated through the Smad-ROS (reactive oxygen species) axis. Disclaimer: AAAS and ...